Abstract The small, hormone-like molecule retinoic acid (RA) Drivetrain is a vital regulator in several neurobiological processes that are affected in depression.Next to its involvement in dopaminergic signal transduction, neuroinflammation, and neuroendocrine regulation, recent studies highlight the role of RA in homeostatic synaptic plasticity an
Solriamfetol impurities: Synthesis, characterization, and analytical method (UPLC-UV) validation
Given that impurities may affect the quality and safety of drug products, impurity identification and profiling is an integral part of drug quality control and is particularly important for newly developed medications such as solriamfetol, which is used to treat excessive daytime sleepiness.Although the high-performance liquid chromatography analys
Anti-MDA5 Antibody-Positive Dermatomyositis Presenting with Cellulitis-Like Erythema on the Mandible as an Initial Symptom
Panniculitis is an uncommon skin eruption observed in patients with dermatomyositis (DM)/clinically amyopathic dermatomyositis (CADM), especially in anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive DM.We present here a 51-year-old Japanese woman with an anti-MDA5 antibody-positive DM who initially had cellulitis-like erythem
ELECTRONIC CIRCUIT BOARDS NON-UNIFORM COOLING SYSTEM MODEL
Abstract.The paper considers a mathematical model of non-uniform cooling of electronic circuit boards.The block diagram of the system implementing this approach, the method of calculation of the electronic board temperature field, as well as the principle of its thermal performance optimizing are presented.In the considered scheme the main heat eli